Haemostatic, resorbable dual-use dressings

research under the Intelligent Development Operational Programme, POIR.04.01.02-00-0004/17

The aim of the project is to develop and implement a universal, complementary dressing kit consisting of four subsets for the protection of permanent injuries.

The innovative, universal and complementary dressing set will consist of:
(1) an absorbent dressing integrated with a bandage,
(2) a tampon designed for gunshot and stab wounds,
(3) non-woven material,
(4) a tactical strop.

 

(1) Resorbable dressing made from a mixture of amino acid/peptide-modified alginate and chitosan fibres integrated into a bandage for the treatment of heavily bleeding wounds.

(2) Resorbable fibre tampon, a mixture of amino acid/peptide modified chitosan fibres or chitosan and calcium alginate derivatives. Haemostatic and antimicrobial effect (presence of microsilver). Resorbable product. Simple operation and easy removal of the tampon. Possibility of stopping bleeding from gunshot wounds and stab wounds.

(3) Gauze/woven fabric. A product made from resorbable materials. A non-woven fabric or gauze placed directly over a bleeding wound to stop the bleeding in a very short time. The material used to make the gauze/non-woven fabric will consist of peptide/amino acid modified haemostatic chitosan or alginate fibres.

(4) The tactical stasis will be made of a plastic suitable for the purpose and will be designed to achieve the appropriate level of compression without the involvement of specially trained people.

These dressings will be of particular use to uniformed services and civilians. The final dressings and their use are intended to meet the operational requirements of Stage 1 and 2 medical evacuation for the Polish Armed Forces and the corresponding levels of field medical assistance provided by other uniformed services or civilian units.

The proposed universal, complementary dressing kit should also be standard equipment for civilian services. It also seems reasonable to introduce the developed set into the equipment of basic medical aid kits in production plants, where there is an increased risk of accidents resulting in permanent injuries. The proposed solution can be used as an element of a set of standard dressings, including, among others, dressing gauze or bandages, which, despite representing the largest quantitative share of the medical devices market, are not sufficient components from the point of view of heavily bleeding injuries. The fundamental premise of the proposed solution is to stop bleeding within 2-3 min. This effect is possible due to the haemostatic properties of the sugar materials themselves and is supported by the use of amino acids/peptides modified with haemostatic properties. In addition, the proposed solution uses technologies that guarantee protection against infection by pathogenic microorganisms.

 

The project is carried out by a consortium comprising:

– Lodz University of Technology, Faculty of Chemistry and Faculty of Material Technologies
Technology and Textile Design,
– Bella Sp. z o.o,
– TRICOMED SA,
– Military Institute of Hygiene and Epidemiology.