Analytical services

– see what we can do for you

1) Synthesis of libraries of peptides, lipopeptides and protein fragments by the SPOT technique

  • SPOT Synthesizer – Parallel Peptide Synthesizer MultiPep RSi Intavis Bioanalytical Instrument
  • SPOT Synthesizer – Parallel Peptide Synthesizer Bioanalytical Instrument

2) Synthesis of “difficult” peptides, amides, esters in solution and on solid phase

  • Synthesizer – Heidolph Synthesis 1 Solid System with Wastebox
  • Synthesiser – LibertyBlue CEM automated microwave peptide synthesiser
  • HPLC kit – Gilson prepELS II detector, Waters 2489 UV/Visible detector, Waters 600S controller, Waters 717 autosampler, Waters 616 pump, Waters 2487 Dual λ absorption detector
  • HPLC-DAD-MS kit – Diodex UltiMate 3000 UHPLC focused: pump, autosampler, diode array detection
  • Preparative chromatograph – Combi Flesh EZ prep UV-VIS Teldyn ISCO
  • Lyophilizer – Labconco FreeZone 1
  • Labconco Cooled CentriVap Conetrator

3) Synthesis of structurally diverse compounds on both the small scale and the enlarged scale

  • Discover microwave reactor from CEM with compressor and professional software
  • 10-litre Reactor-Ready Pilot fusion reactor from Radleys fitted with a stirrer from Heidolph and complete with Presto Julabo A40 temperature control unit and laptop with software

4) Compound analyses by GC-MS MS, UV and CD

  • GC-MS Kit – PerkinsElmer Mass Spectromer Clarus SQ 8 S, PerkinsElmer Gas Chromatograph Clarus 580, PerkinsElmer Headspace Sampler TurboMatrix 40 Trap
  • Bruker micrOTOF-Q III
  • MS spectrometer (MALDI-TOF) – ultrafleXtreme, with sprayer – TM-Sprayer HTXImaging by HTX Technologies LLC together with scanner – Bruker TissueScout,
  • UV-VIS spectroscope – UV-1601 UV-Visible spectrophotometer Shimadzu
  • UV-VIS spectroscope – Thermo Scientific Orion AquaMate 8000 UV/Vis spectrophotometer
  • CD spectrometer – Jasco J-1500