PhD. Eng.

Justyna Frączyk



Doctoral degree in chemistry, discipline
chemistry, Department of Chemistry Technical
University of Lodz


Doctoral degree in chemistry, Department of Chemistry
Technical University of Lodz


Master of Engineering, majoring in EngineeringMaterials,
Department of Chemistry Technical University of Lodz



Assistant Professor – Institute of Organic Chemistry, Technical University of Lodz


Assistant – Institute of Organic Chemistry, Technical University of Lodz

Scientific interests

  • Design, synthesis and application of peptides/lipopeptides immobilised on solid supports as useful tools for medical diagnostics

Various molecular approaches and tools are being used in research to develop methods useful for the rapid, sensitive diagnosis of oncological, autoimmune and neurodegenerative diseases. One of these is molecular receptors and peptides immobilised on cellulose allowing specific binding of potential biomarkers (low molecular weight, polypeptide, protein) of a given disease present in physiological fluids (urine, blood, cerebrospinal fluid, tissue homogenates). The developed solution has found application in the search for diagnostic/prognostic biomarkers of cancer (thyroid cancer, C38 colon cancer, 16/C breast cancer, LLC lung cancer), autoimmune diseases (RA rheumatoid arthritis, arteriosclerosis), neurodegenerative diseases (Parkinson’s, Alzheimer’s diseases) and coronary heart disease.

  • Design and synthesis of nanoparticle conjugates – new therapeutic approaches

Nanomaterials are widely used in medicine. Our research focuses on the development of new methods for the functionalisation of nanomaterials, allowing conjugates with significantly improved application properties to be obtained. The research is focused on the creation of derivatives containing a therapeutic fragment attached to the nanoparticle, as well as structural fragments that improve selectivity in reaching pathological sites and improve permeation through cell membranes. Conjugates of nanomaterials with a drug and a homing fragment can be used in cancer therapy. If magnetic nanoparticles are used, they can also be used as materials in thermoablation.

Selected publications

  1. J. Fraczyk, Z.J. Kaminski, “Designing, synthesis and application of a library of supramolecular structures formed by N-lipidated peptides immobilized on cellulose. Artificial receptors” J. Comb. Chem. 2008, 10, 934-940,


  1. J. Fraczyk, B. Kolesinska, A. Czarnecka, B. Malawska, A. Wieckowska, M. Bajda, Z.J. Kaminski, “The application of a library of artificial receptors formed by the self-organization of N-lipidated peptides immobilized on cellulose for preliminary studies of binding of N-phenylpiperazines” QSAR & Comb. Sci. 2009, 28, 728-736,



  1. J. Fraczyk, B. Kolesinska, Z.J. Kaminski, “N-lipidated oligopeptides immobilized on cellulose as new type of organocatalysts” J. Comb. Chem. & H.T.S. 2013, 16, 562-571,


  1. A. Bak, M. Daszykowski, Z. Kaminski, K. Kiec- Kononowicz, K. Kuder, J. Fraczyk, B. Kolesinska, P. Ciosek, J. Polanski, “Probing an Artificial Polypeptide Receptor Library Using a Series of Novel Histamine H3 Receptor Ligands” J. Comb. Chem. & H.T.S. 2014, 17, 141-156,


  1. J. Fraczyk, M. Walczak, L. Szymanski, Z. Kolacinski, H. Wrzosek, I. Majsterek, K. Przybylowska-Sygut, Z.J. Kaminski, “Carbon nanotubes functionalized with folic acid attached via biomimetic peptide linker” Nanomedicine, 2017, 12, 2161–2182,


  1. J. Fraczyk, M. Walczak, Z.J. Kaminski, “New Methodology for Automated SPOT Synthesis of Peptides on Cellulose using 1,3,5-Triazine derivatives as Linkers and as Coupling Reagents” J. Pep. Sci. 2018, 24, e3063,


  1. J. Fraczyk, A. Rosowski, B. Kolesinska, A. Koperkiewcz, A. Sobczyk-Guzenda, Z.J. Kaminski, M. Dudek, “Orthogonal Functionalization of Nanodiamond Particles after Laser Modification and Treatment with Aromatic Amine Derivatives” Nanomaterials, 2018, 8, 908,


  1. J. Fraczyk, Z.J. Kaminski, “N-Lipidated Amino Acids and Peptides Immobilized on Cellulose Able to Split Amide Bonds” Materials, 2019, 12, 578,


9. K. Wojtera, M. Walczak, L. Pietrzak, J. Fraczyk, Ł. Szymański, A. Sobczyk-Guzenda, “Synthesis of functionalized carbon nanotubes for fluorescent biosensors” Nanotechnology Reviews, 9, 1237-1244 (2020)